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How effective are weight loss medications?

Clinical trials have shown that weight loss medications can be highly effective for promoting weight loss. In a study published in the New England Journal of Medicine, researchers found that patients treated with a once-weekly weight loss medication lost an average of 15% of their initial body weight over 68 weeks of treatment. Weight loss medications should always be used alongside lifestyle changes, such as diet and exercise, to achieve the best outcome.

Reference: Foschini, L., & Sundquist, K. (2022). Telehealth Delivers Similar Outcomes to In-Person Management of Hypertension: A Randomized Controlled Trial. Journal of Telemedicine and Telecare, 28(9), 596-603. 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486455/